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CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2

CD44 shedding occurs in osteoarthritic chondrocytes. Previous work of others has suggested that the hyaluronidase isoform HYAL2 has the capacity to bind to CD44, a binding that may itself induce CD44 cleavage. Experiments were developed to elucidate whether chondrocyte HYAL2: (1) was exposed on the...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Hida, Daisuke, Danielson, Ben T., Knudson, Cheryl B., Knudson, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600047/
https://ncbi.nlm.nih.gov/pubmed/25864644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.04.002
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