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CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2

CD44 shedding occurs in osteoarthritic chondrocytes. Previous work of others has suggested that the hyaluronidase isoform HYAL2 has the capacity to bind to CD44, a binding that may itself induce CD44 cleavage. Experiments were developed to elucidate whether chondrocyte HYAL2: (1) was exposed on the...

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Publicado en:Matrix Biol
Autores principales: Hida, Daisuke, Danielson, Ben T., Knudson, Cheryl B., Knudson, Warren
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600047/
https://ncbi.nlm.nih.gov/pubmed/25864644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.04.002
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