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CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2

CD44 shedding occurs in osteoarthritic chondrocytes. Previous work of others has suggested that the hyaluronidase isoform HYAL2 has the capacity to bind to CD44, a binding that may itself induce CD44 cleavage. Experiments were developed to elucidate whether chondrocyte HYAL2: (1) was exposed on the...

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Dettagli Bibliografici
Pubblicato in:Matrix Biol
Autori principali: Hida, Daisuke, Danielson, Ben T., Knudson, Cheryl B., Knudson, Warren
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600047/
https://ncbi.nlm.nih.gov/pubmed/25864644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.04.002
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