Intracellular Domain Fragment of CD44 Alters CD44 Function in Chondrocytes

The hyaluronan receptor CD44 undergoes sequential proteolytic cleavage at the cell surface. The initial cleavage of the CD44 extracellular domain is followed by a second intramembranous cleavage of the residual CD44 fragment, liberating the C-terminal cytoplasmic tail of CD44. In this study conditio...

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Библиографические подробности
Главные авторы: Mellor, Liliana, Knudson, Cheryl B., Hida, Daisuke, Askew, Emily B., Knudson, Warren
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Glycobiology and Extracellular Matrices
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764790/
https://ncbi.nlm.nih.gov/pubmed/23884413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494872
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