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Intracellular Domain Fragment of CD44 Alters CD44 Function in Chondrocytes

The hyaluronan receptor CD44 undergoes sequential proteolytic cleavage at the cell surface. The initial cleavage of the CD44 extracellular domain is followed by a second intramembranous cleavage of the residual CD44 fragment, liberating the C-terminal cytoplasmic tail of CD44. In this study conditio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mellor, Liliana, Knudson, Cheryl B., Hida, Daisuke, Askew, Emily B., Knudson, Warren
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764790/
https://ncbi.nlm.nih.gov/pubmed/23884413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494872
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