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Intracellular Domain Fragment of CD44 Alters CD44 Function in Chondrocytes

The hyaluronan receptor CD44 undergoes sequential proteolytic cleavage at the cell surface. The initial cleavage of the CD44 extracellular domain is followed by a second intramembranous cleavage of the residual CD44 fragment, liberating the C-terminal cytoplasmic tail of CD44. In this study conditio...

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Detalhes bibliográficos
Main Authors: Mellor, Liliana, Knudson, Cheryl B., Hida, Daisuke, Askew, Emily B., Knudson, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764790/
https://ncbi.nlm.nih.gov/pubmed/23884413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494872
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