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Designing herpes viruses as oncolytics

Oncolytic herpes simplex virus (oHSV) was one of the first genetically-engineered oncolytic viruses. Because HSV is a natural human pathogen that can cause serious disease, it is incumbent that it can be genetically-engineered or significantly attenuated for safety. Here, we present a detailed expla...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Peters, Cole, Rabkin, Samuel D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599707/
https://ncbi.nlm.nih.gov/pubmed/26462293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.10
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