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Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms

Alterations in the glial function of TDP-43 are becoming increasingly associated with the neurological symptoms observed in Amyotrophic Lateral Sclerosis (ALS), however, the physiological role of this protein in the glia or the mechanisms that may lead to neurodegeneration are unknown. To address th...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Romano, Giulia, Appocher, Chiara, Scorzeto, Michele, Klima, Raffaella, Baralle, Francisco E., Megighian, Aram, Feiguin, Fabian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599672/
https://ncbi.nlm.nih.gov/pubmed/26276811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv330
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