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Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms

Alterations in the glial function of TDP-43 are becoming increasingly associated with the neurological symptoms observed in Amyotrophic Lateral Sclerosis (ALS), however, the physiological role of this protein in the glia or the mechanisms that may lead to neurodegeneration are unknown. To address th...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Romano, Giulia, Appocher, Chiara, Scorzeto, Michele, Klima, Raffaella, Baralle, Francisco E., Megighian, Aram, Feiguin, Fabian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599672/
https://ncbi.nlm.nih.gov/pubmed/26276811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv330
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