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Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms

Alterations in the glial function of TDP-43 are becoming increasingly associated with the neurological symptoms observed in Amyotrophic Lateral Sclerosis (ALS), however, the physiological role of this protein in the glia or the mechanisms that may lead to neurodegeneration are unknown. To address th...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Romano, Giulia, Appocher, Chiara, Scorzeto, Michele, Klima, Raffaella, Baralle, Francisco E., Megighian, Aram, Feiguin, Fabian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599672/
https://ncbi.nlm.nih.gov/pubmed/26276811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv330
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