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Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms

Alterations in the glial function of TDP-43 are becoming increasingly associated with the neurological symptoms observed in Amyotrophic Lateral Sclerosis (ALS), however, the physiological role of this protein in the glia or the mechanisms that may lead to neurodegeneration are unknown. To address th...

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Détails bibliographiques
Publié dans:Hum Mol Genet
Auteurs principaux: Romano, Giulia, Appocher, Chiara, Scorzeto, Michele, Klima, Raffaella, Baralle, Francisco E., Megighian, Aram, Feiguin, Fabian
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599672/
https://ncbi.nlm.nih.gov/pubmed/26276811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv330
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