Evolutionarily Conserved Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A/B Proteins Functionally Interact with Human and Drosophila TAR DNA-binding Protein 43 (TDP-43)

Human TDP-43 represents the main component of neuronal inclusions found in patients with neurodegenerative diseases, especially frontotemporal lobar degeneration and amyotrophic lateral sclerosis. In vitro and in vivo studies have shown that the TAR DNA-binding protein 43 (TDP-43) Drosophila ortholo...

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Detalhes bibliográficos
Main Authors: Romano, Maurizio, Buratti, Emanuele, Romano, Giulia, Klima, Raffaella, Del Bel Belluz, Lisa, Stuani, Cristiana, Baralle, Francisco, Feiguin, Fabian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945372/
https://ncbi.nlm.nih.gov/pubmed/24492607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548859
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