Evolutionarily Conserved Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A/B Proteins Functionally Interact with Human and Drosophila TAR DNA-binding Protein 43 (TDP-43)

Human TDP-43 represents the main component of neuronal inclusions found in patients with neurodegenerative diseases, especially frontotemporal lobar degeneration and amyotrophic lateral sclerosis. In vitro and in vivo studies have shown that the TAR DNA-binding protein 43 (TDP-43) Drosophila ortholo...

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Bibliographische Detailangaben
Hauptverfasser: Romano, Maurizio, Buratti, Emanuele, Romano, Giulia, Klima, Raffaella, Del Bel Belluz, Lisa, Stuani, Cristiana, Baralle, Francisco, Feiguin, Fabian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945372/
https://ncbi.nlm.nih.gov/pubmed/24492607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548859
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