Calcium/Calmodulin-Dependent Kinase II Inhibition in Smooth Muscle Reduces Angiotensin II–Induced Hypertension by Controlling Aortic Remodeling and Baroreceptor Function

BACKGROUND: Multifunctional calcium/calmodulin-dependent kinase II (CaMKII) is activated by angiotensin II (Ang II) in cultured vascular smooth muscle cells (VSMCs), but its function in experimental hypertension has not been explored. The aim of this study was to determine the impact of CaMKII inhib...

詳細記述

保存先:
書誌詳細
出版年:J Am Heart Assoc
主要な著者: Prasad, Anand M, Morgan, Donald A, Nuno, Daniel W, Ketsawatsomkron, Pimonrat, Bair, Thomas B, Venema, Ashlee N, Dibbern, Megan E, Kutschke, William J, Weiss, Robert M, Lamping, Kathryn G, Chapleau, Mark W, Sigmund, Curt D, Rahmouni, Kamal, Grumbach, Isabella M
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Ltd 2015
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599535/
https://ncbi.nlm.nih.gov/pubmed/26077587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.001949
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