Calcium/Calmodulin-Dependent Kinase II Inhibition in Smooth Muscle Reduces Angiotensin II–Induced Hypertension by Controlling Aortic Remodeling and Baroreceptor Function

BACKGROUND: Multifunctional calcium/calmodulin-dependent kinase II (CaMKII) is activated by angiotensin II (Ang II) in cultured vascular smooth muscle cells (VSMCs), but its function in experimental hypertension has not been explored. The aim of this study was to determine the impact of CaMKII inhib...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Heart Assoc
मुख्य लेखकों: Prasad, Anand M, Morgan, Donald A, Nuno, Daniel W, Ketsawatsomkron, Pimonrat, Bair, Thomas B, Venema, Ashlee N, Dibbern, Megan E, Kutschke, William J, Weiss, Robert M, Lamping, Kathryn G, Chapleau, Mark W, Sigmund, Curt D, Rahmouni, Kamal, Grumbach, Isabella M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley & Sons, Ltd 2015
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599535/
https://ncbi.nlm.nih.gov/pubmed/26077587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.001949
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