Differential Control of Calcium Homeostasis and Vascular Reactivity by CaMKII

The multifunctional calcium/calmodulin-dependent kinase II (CaMKII) is activated by vasoconstrictors in vascular smooth muscle cells (VSMC), but its impact on vasoconstriction remains unknown. We hypothesized that CaMKII inhibition in VSMC decreases vasoconstriction. Using novel transgenic mice that...

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Detalhes bibliográficos
Main Authors: Prasad, Anand M., Nuno, Daniel W., Koval, Olha M., Ketsawatsomkron, Pimonrat, Li, Weiwei, Li, Hui, Shen, Fred Y., Joiner, Mei-ling A., Kutschke, William, Weiss, Robert M., Sigmund, Curt D., Anderson, Mark E., Lamping, Kathryn G., Grumbach, Isabella M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868483/
https://ncbi.nlm.nih.gov/pubmed/23753415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01508
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