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Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection

Connexins are widely distributed proteins in the body that are crucially important for heart and brain function. Six connexin subunits form a connexon or hemichannel in the plasma membrane. Interactions between two hemichannels in a head-to-head arrangement result in the formation of a gap junction...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Ther
Hauptverfasser: Schulz, Rainer, Görge, Philipp Maximilian, Görbe, Anikó, Ferdinandy, Péter, Lampe, Paul D., Leybaert, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599355/
https://ncbi.nlm.nih.gov/pubmed/26073311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.06.005
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