Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning

Myocardial connexin 43 (Cx43) forms gap junctions and hemichannels, and is also present within subsarcolemmal mitochondria. The protein is phosphorylated by several kinases including mitogen-activated protein kinase (MAPK), protein kinase C (PKC), and casein kinase 1 (CK1). A reduction in Cx43 conte...

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Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Hirschhäuser, Christine, Lissoni, Alessio, Görge, Philipp Maximilian, Lampe, Paul D., Heger, Jacqueline, Schlüter, Klaus-Dieter, Leybaert, Luc, Schulz, Rainer, Boengler, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985055/
https://ncbi.nlm.nih.gov/pubmed/33751227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-021-00861-z
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