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Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
Connexin43 (Cx43) function is influenced by kinases that phosphorylate specific serine sites located near its C-terminus. Stroke is a powerful inducer of kinase activity, but its effect on Cx43 is unknown. We investigated the impact of wild-type (WT) and knock-in Cx43 with serine to alanine mutation...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446879/ https://ncbi.nlm.nih.gov/pubmed/30872361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171452 |
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