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Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke

Connexin43 (Cx43) function is influenced by kinases that phosphorylate specific serine sites located near its C-terminus. Stroke is a powerful inducer of kinase activity, but its effect on Cx43 is unknown. We investigated the impact of wild-type (WT) and knock-in Cx43 with serine to alanine mutation...

詳細記述

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書誌詳細
出版年:J Exp Med
主要な著者: Freitas-Andrade, Moises, Wang, Nan, Bechberger, John F., De Bock, Marijke, Lampe, Paul D., Leybaert, Luc, Naus, Christian C.
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446879/
https://ncbi.nlm.nih.gov/pubmed/30872361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171452
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