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A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive, metastatic disease with limited treatment options. Factors contributing to the metastatic predisposition and therapy resistance in pancreatic cancer are not well understood. Here, we used a mouse model of KRAS-driven pancreatic carcinog...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Ischenko, Irene, Petrenko, Oleksi, Hayman, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599239/
https://ncbi.nlm.nih.gov/pubmed/26158412
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