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Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells

The hematopoietic cell kinase (HCK) is a member of the SRC family of cytoplasmic tyrosine kinases (SFKs), and is expressed in cells of the myeloid and B-lymphocyte cell lineages. Excessive HCK activation is associated with several types of leukemia and enhances cell proliferation and survival by phy...

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Publicado en:Oncotarget
Autores principales: Poh, Ashleigh R., O'Donoghue, Robert J.J., Ernst, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599235/
https://ncbi.nlm.nih.gov/pubmed/26087188
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