Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process

The Saccharomyces cerevisiae heat shock protein Hsp31 is a stress-inducible homodimeric protein that is involved in diauxic shift reprogramming and has glyoxalase activity. We show that substoichiometric concentrations of Hsp31 can abrogate aggregation of a broad array of substrates in vitro. Hsp31...

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Udgivet i:J Biol Chem
Main Authors: Tsai, Chai-jui, Aslam, Kiran, Drendel, Holli M., Asiago, Josephat M., Goode, Kourtney M., Paul, Lake N., Rochet, Jean-Christophe, Hazbun, Tony R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598993/
https://ncbi.nlm.nih.gov/pubmed/26306045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678367
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