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The small heat shock protein Hsp31 cooperates with Hsp104 to modulate Sup35 prion aggregation

The yeast homolog of DJ-1, Hsp31, is a multifunctional protein that is involved in several cellular pathways including detoxification of the toxic metabolite methylglyoxal and as a protein deglycase. Prior studies ascribed Hsp31 as a molecular chaperone that can inhibit α-Syn aggregation in vitro an...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Aslam, Kiran, Tsai, Chai-jui, Hazbun, Tony R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161301/
https://ncbi.nlm.nih.gov/pubmed/27690738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2016.1234574
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