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An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products

Bacterial natural products are a diverse and valuable group of small molecules, and genome sequencing indicates that the vast majority remain undiscovered. The prediction of natural product structures from biosynthetic assembly lines can facilitate their discovery, but highly automated, accurate, an...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Johnston, Chad W., Skinnider, Michael A., Wyatt, Morgan A., Li, Xiang, Ranieri, Michael R. M., Yang, Lian, Zechel, David L., Ma, Bin, Magarvey, Nathan A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598715/
https://ncbi.nlm.nih.gov/pubmed/26412281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9421
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