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Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery

Nonribosomal peptides are highly sought after for their therapeutic applications. As with other natural products, dereplication of known compounds and focused discovery of new agents within this class are central concerns of modern natural product-based drug discovery. Development of a chemoinformat...

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Detalhes bibliográficos
Main Authors: Ibrahim, Ashraf, Yang, Lian, Johnston, Chad, Liu, Xiaowen, Ma, Bin, Magarvey, Nathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511102/
https://ncbi.nlm.nih.gov/pubmed/23132949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206376109
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