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An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products

Bacterial natural products are a diverse and valuable group of small molecules, and genome sequencing indicates that the vast majority remain undiscovered. The prediction of natural product structures from biosynthetic assembly lines can facilitate their discovery, but highly automated, accurate, an...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Johnston, Chad W., Skinnider, Michael A., Wyatt, Morgan A., Li, Xiang, Ranieri, Michael R. M., Yang, Lian, Zechel, David L., Ma, Bin, Magarvey, Nathan A.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598715/
https://ncbi.nlm.nih.gov/pubmed/26412281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9421
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