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An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products

Bacterial natural products are a diverse and valuable group of small molecules, and genome sequencing indicates that the vast majority remain undiscovered. The prediction of natural product structures from biosynthetic assembly lines can facilitate their discovery, but highly automated, accurate, an...

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Detalles Bibliográficos
Publicado en:Nat Commun
Autores principales: Johnston, Chad W., Skinnider, Michael A., Wyatt, Morgan A., Li, Xiang, Ranieri, Michael R. M., Yang, Lian, Zechel, David L., Ma, Bin, Magarvey, Nathan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598715/
https://ncbi.nlm.nih.gov/pubmed/26412281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9421
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