A Duplicated ESAT-6 Region of ESX-5 Is Involved in Protein Export and Virulence of Mycobacteria

The ESX-5 secretion system of Mycobacterium tuberculosis is important for bacterial virulence and for the secretion of the large PE/PPE protein family, whose genes constitute 10% of the M. tuberculosis genome. A four-gene region of the ESX-5 system is duplicated three times in the M. tuberculosis ge...

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Shah, Swati, Cannon, Joe R., Fenselau, Catherine, Briken, Volker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Molecular Pathogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598393/
https://ncbi.nlm.nih.gov/pubmed/26303392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00827-15
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