The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Mycobacteria produce a capsule layer, which consists of glycan-like polysaccharides and a number of specific proteins. In this study, we show that, in slow-growing mycobacteria, the type VII secretion system ESX-5 plays a major role in the integrity and stability of the capsule. We have identified P...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ates, Louis S., van der Woude, Aniek D., Bestebroer, Jovanka, van Stempvoort, Gunny, Musters, René J. P., Garcia-Vallejo, Juan J., Picavet, Daisy I., van de Weerd, Robert, Maletta, Massimiliano, Kuijl, Coenraad P., van der Wel, Nicole N., Bitter, Wilbert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900558/
https://ncbi.nlm.nih.gov/pubmed/27280885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005696
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