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Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway

The type VII secretion system ESX-5 is a major pathway for export of PE and PPE proteins in pathogenic mycobacteria. These mycobacteria-specific protein families are characterized by conserved N-terminal domains of 100 and 180 amino acids, which contain the proline-glutamic acid (PE) and proline-pro...

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Detalhes bibliográficos
Main Authors: Daleke, Maria H., Cascioferro, Alessandro, de Punder, Karin, Ummels, Roy, Abdallah, Abdallah M., van der Wel, Nicole, Peters, Peter J., Luirink, Joen, Manganelli, Riccardo, Bitter, Wilbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099717/
https://ncbi.nlm.nih.gov/pubmed/21471225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204966
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