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Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier

BACKGROUND: Mycobacterium bovis Bacille Calmette-Guérin (BCG) is not only used as a vaccine against tuberculosis but also protects against leprosy and is used as part of bladder cancer treatment to induce a protective immune response. However, protection by BCG vaccination is not optimal. To improve...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Burggraaf, Maroeska J., Ates, Louis S., Speer, Alexander, van der Kuij, Kim, Kuijl, Coen, Bitter, Wilbert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402100/
https://ncbi.nlm.nih.gov/pubmed/30841891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1093-1
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