HIV-1 and Human PEG10 Frameshift Elements Are Functionally Distinct and Distinguished by Novel Small Molecule Modulators

Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a second reading frame relative to the structural group-s...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Cardno, Tony S., Shimaki, Yosuke, Sleebs, Brad E., Lackovic, Kurt, Parisot, John P., Moss, Rebecca M., Crowe-McAuliffe, Caillan, Mathew, Suneeth F., Edgar, Christina D., Kleffmann, Torsten, Tate, Warren P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598141/
https://ncbi.nlm.nih.gov/pubmed/26447468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139036
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