Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel

When a stop codon is at the 80S ribosomal A site, there are six nucleotides (+4 to +9) downstream that are inferred to be occupying the mRNA channel. We examined the influence of these downstream nucleotides on translation termination success or failure in mammalian cells at the three stop codons. T...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Cridge, Andrew G, Crowe-McAuliffe, Caillan, Mathew, Suneeth F, Tate, Warren P
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829715/
https://ncbi.nlm.nih.gov/pubmed/29325104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1315
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