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Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel

When a stop codon is at the 80S ribosomal A site, there are six nucleotides (+4 to +9) downstream that are inferred to be occupying the mRNA channel. We examined the influence of these downstream nucleotides on translation termination success or failure in mammalian cells at the three stop codons. T...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Cridge, Andrew G, Crowe-McAuliffe, Caillan, Mathew, Suneeth F, Tate, Warren P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829715/
https://ncbi.nlm.nih.gov/pubmed/29325104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1315
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