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Translation Termination and Ribosome Recycling in Eukaryotes

Termination of mRNA translation occurs when a stop codon enters the A site of the ribosome, and in eukaryotes is mediated by release factors eRF1 and eRF3, which form a ternary eRF1/eRF3–guanosine triphosphate (GTP) complex. eRF1 recognizes the stop codon, and after hydrolysis of GTP by eRF3, mediat...

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Publicat a:Cold Spring Harb Perspect Biol
Autor principal: Hellen, Christopher U.T.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169810/
https://ncbi.nlm.nih.gov/pubmed/29735640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032656
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