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How do oncoprotein mutations rewire protein-protein interaction networks? Perspectives and techniques
The acquisition of mutations that activate oncogenes or inactivate tumour suppressors is a primary feature of most cancers. Mutations that directly alter protein sequence and structure drive the development of tumours through aberrant expression and modification of proteins, in many cases directly i...
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| Veröffentlicht in: | Expert Rev Proteomics |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598059/ https://ncbi.nlm.nih.gov/pubmed/26325016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14789450.2015.1084875 |
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