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Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks

Alternative inclusion of exons increases the functional diversity of proteins. Among alternatively spliced exons, tissue-specific exons play a critical role in maintaining tissue identity. This raises the question of how tissue-specific protein-coding exons influence protein function. Here we invest...

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Detalhes bibliográficos
Main Authors: Buljan, Marija, Chalancon, Guilhem, Eustermann, Sebastian, Wagner, Gunter P., Fuxreiter, Monika, Bateman, Alex, Babu, M. Madan
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437557/
https://ncbi.nlm.nih.gov/pubmed/22749400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.039
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