Protein Disulfide Isomerase-ERp57 regulates allergen-induced airways inflammation, fibrosis and hyperresponsiveness

BACKGROUND: Evidence for association between asthma and the unfolded protein response (UPR) is emerging. ERp57 is an ER localized redox chaperone involved in folding and secretion of glycoproteins. We have previously demonstrated that ERp57 is up regulated in allergen-challenged human and murine lun...

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Опубликовано в: :J Allergy Clin Immunol
Главные авторы: Hoffman, Sidra M., Chapman, David G., Lahue, Karolyn G., Cahoon, Jonathon M., Rattu, Gurkiranjit K., Daphtary, Nirav, Aliyeva, Minara, Fortner, Karen A., Erzurum, Serpil C., Comhair, Suzy A.A., Woodruff, Prescott G., Bhakta, Nirav, Dixon, Anne E., Irvin, Charles G., Janssen-Heininger, Yvonne MW., Poynter, Matthew E., Anathy, Vikas
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597791/
https://ncbi.nlm.nih.gov/pubmed/26435004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.08.018
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