Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation

NF-κB signaling plays a crucial role in regulating proliferation and differentiation in the epidermis. Alterations in the NF-κB pathway can lead to skin pathologies with a significant burden to human health such as psoriasis and cutaneous squamous cell carcinoma (cSCC). Caspase recruitment domain (C...

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Dades bibliogràfiques
Publicat a:Am J Pathol
Autors principals: Watt, Stephen A., Purdie, Karin J., den Breems, Nicoline Y., Dimon, Michelle, Arron, Sarah T., McHugh, Angela T., Xue, Dylan J., Dayal, Jasbani H.S., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., South, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2015
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597276/
https://ncbi.nlm.nih.gov/pubmed/26212909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.05.018
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