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Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart. We show that, during cardiac differentiation, the two transcription factors have partially overlapping expression patterns, with the result that as cardiac pro...

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Publicat a:Cell Rep
Autors principals: Dupays, Laurent, Shang, Catherine, Wilson, Robert, Kotecha, Surendra, Wood, Sophie, Towers, Norma, Mohun, Timothy
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597108/
https://ncbi.nlm.nih.gov/pubmed/26411676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.065
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