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Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart. We show that, during cardiac differentiation, the two transcription factors have partially overlapping expression patterns, with the result that as cardiac pro...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Dupays, Laurent, Shang, Catherine, Wilson, Robert, Kotecha, Surendra, Wood, Sophie, Towers, Norma, Mohun, Timothy
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597108/
https://ncbi.nlm.nih.gov/pubmed/26411676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.065
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