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Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function

The homeodomain transcription factor NKX2-5 is known to be essential for both normal heart development and for heart function. But little is yet known about the identities of its downstream effectors or their function during differentiation of cardiac progenitor cells (CPCs). We have used transgenic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dupays, Laurent, Towers, Norma, Wood, Sophie, David, Anna, Stuckey, Daniel J., Mohun, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402701/
https://ncbi.nlm.nih.gov/pubmed/30840660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212992
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