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Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart. We show that, during cardiac differentiation, the two transcription factors have partially overlapping expression patterns, with the result that as cardiac pro...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Dupays, Laurent, Shang, Catherine, Wilson, Robert, Kotecha, Surendra, Wood, Sophie, Towers, Norma, Mohun, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597108/
https://ncbi.nlm.nih.gov/pubmed/26411676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.065
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