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KCl -Permeabilized Pancreatic Islets: An Experimental Model to Explore the Messenger Role of ATP in the Mechanism of Insulin Secretion

Our previous work has demonstrated that islet depolarization with KCl opens connexin36 hemichannels in β-cells of mouse pancreatic islets allowing the exchange of small metabolites with the extracellular medium. In this study, the opening of these hemichannels has been further characterized in rat i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Pizarro-Delgado, Javier, Deeney, Jude T., Martín-del-Río, Rafael, Corkey, Barbara E., Tamarit-Rodriguez, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596849/
https://ncbi.nlm.nih.gov/pubmed/26444014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140096
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