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KCl -Permeabilized Pancreatic Islets: An Experimental Model to Explore the Messenger Role of ATP in the Mechanism of Insulin Secretion

Our previous work has demonstrated that islet depolarization with KCl opens connexin36 hemichannels in β-cells of mouse pancreatic islets allowing the exchange of small metabolites with the extracellular medium. In this study, the opening of these hemichannels has been further characterized in rat i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pizarro-Delgado, Javier, Deeney, Jude T., Martín-del-Río, Rafael, Corkey, Barbara E., Tamarit-Rodriguez, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596849/
https://ncbi.nlm.nih.gov/pubmed/26444014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140096
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