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Differential expression of PD-L1 between primary and metastatic sites in clear cell Renal Cell Carcinoma

PD-L1 expression in primary clear cell renal cell carcinoma (ccRCC) increases the likelihood of response to anti-PD-1 inhibition, but fails to identify all responders. We hypothesized that PD-L1 levels assessed in randomly selected areas of the primary tumors may not accurately reflect expression le...

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Dettagli Bibliografici
Pubblicato in:Cancer Immunol Res
Autori principali: Callea, Marcella, Albiges, Laurence, Gupta, Mamta, Cheng, Su-Chun, Genega, Elizabeth M., Fay, André P., Song, Jiaxi, Carvo, Ingrid, Bhatt, Rupal S., Atkins, Michael B., Hodi, F. Stephen, Choueiri, Toni K., McDermott, David F., Freeman, Gordon J., Signoretti, Sabina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596765/
https://ncbi.nlm.nih.gov/pubmed/26014095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0043
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