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Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Advances in next-generation sequencing have provided a unique opportunity to understand the biology of disease and mechanisms of sensitivity or resistance to specific agents. Renal cell carcinoma (RCC) is a heterogeneous disease and highly variable clinical responses have been observed with vascular...

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Detalhes bibliográficos
Publicado no:J Natl Compr Canc Netw
Main Authors: Fay, Andre P., de Velasco, Guillermo, Ho, Thai H., Van Allen, Eliezer M., Murray, Bradley, Albiges, Laurence, Signoretti, Sabina, Hakimi, A. Ari, Stanton, Melissa L., Bellmunt, Joaquim, McDermott, David F., Atkins, Michael B., Garraway, Levi A., Kwiatkowski, David J., Choueiri, Toni K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582541/
https://ncbi.nlm.nih.gov/pubmed/27407122
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