Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Advances in next-generation sequencing have provided a unique opportunity to understand the biology of disease and mechanisms of sensitivity or resistance to specific agents. Renal cell carcinoma (RCC) is a heterogeneous disease and highly variable clinical responses have been observed with vascular...

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Publicat a:J Natl Compr Canc Netw
Autors principals: Fay, Andre P., de Velasco, Guillermo, Ho, Thai H., Van Allen, Eliezer M., Murray, Bradley, Albiges, Laurence, Signoretti, Sabina, Hakimi, A. Ari, Stanton, Melissa L., Bellmunt, Joaquim, McDermott, David F., Atkins, Michael B., Garraway, Levi A., Kwiatkowski, David J., Choueiri, Toni K.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582541/
https://ncbi.nlm.nih.gov/pubmed/27407122
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