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Differential expression of c-Met between primary and metastatic sites in clear-cell renal cell carcinoma and its association with PD-L1 expression

In preclinical models, c-Met promotes survival of renal cancer cells through the regulation of programmed death-ligand 1 (PD-L1). However, this relationship in human clear cell renal cell carcinoma (ccRCC) is not well characterized. We evaluated c-Met expression in ccRCC patients using paired primar...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lalani, Aly-Khan A., Gray, Kathryn P., Albiges, Laurence, Callea, Marcella, Pignon, Jean-Christophe, Pal, Soumitro, Gupta, Mamta, Bhatt, Rupal S., McDermott, David F., Atkins, Michael B., Woude, G.F. Vande, Harshman, Lauren C., Choueiri, Toni K., Signoretti, Sabina
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732739/
https://ncbi.nlm.nih.gov/pubmed/29262573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21952
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