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Correlation of Apobec Mrna Expression with overall Survival and pd-l1 Expression in Urothelial Carcinoma

Metastatic urothelial carcinoma (mUC) has a very high mutational rate and is associated with an APOBEC mutation signature. We examined the correlation of APOBEC expression with overall survival (OS) and PD-L1 expression in a cohort of 73 mUC patients. mRNA expression of APOBEC3 family of genes (A3A,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mullane, Stephanie A., Werner, Lillian, Rosenberg, Jonathan, Signoretti, Sabina, Callea, Marcella, Choueiri, Toni K., Freeman, Gordon J., Bellmunt, Joaquim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901342/
https://ncbi.nlm.nih.gov/pubmed/27283319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27702
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