Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation

Genetic studies have to date identified 43 genome wide significant coeliac disease susceptibility (CD) loci comprising over 70 candidate genes. However, how altered regulation of such disease associated genes contributes to CD pathogenesis remains to be elucidated. Recently there has been considerab...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Quinn, Emma M., Coleman, Ciara, Molloy, Ben, Dominguez Castro, Patricia, Cormican, Paul, Trimble, Valerie, Mahmud, Nasir, McManus, Ross
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596691/
https://ncbi.nlm.nih.gov/pubmed/26444573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140049
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