Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci

Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It has an estimated prevalence of approximately 1% in European populations. Specific HLA-DQA1 and HLA-DQB1 alleles are established coeliac susceptibility genes and are required for the presentation of gli...

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Publicado no:Eur J Hum Genet
Main Authors: Coleman, Ciara, Quinn, Emma M, Ryan, Anthony W, Conroy, Judith, Trimble, Valerie, Mahmud, Nasir, Kennedy, Nicholas, Corvin, Aiden P, Morris, Derek W, Donohoe, Gary, O'Morain, Colm, MacMathuna, Padraic, Byrnes, Valerie, Kiat, Clifford, Trynka, Gosia, Wijmenga, Cisca, Kelleher, Dermot, Ennis, Sean, Anney, Richard JL, McManus, Ross
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717209/
https://ncbi.nlm.nih.gov/pubmed/25920553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.87
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