Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci

Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It has an estimated prevalence of approximately 1% in European populations. Specific HLA-DQA1 and HLA-DQB1 alleles are established coeliac susceptibility genes and are required for the presentation of gli...

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Veröffentlicht in:Eur J Hum Genet
Hauptverfasser: Coleman, Ciara, Quinn, Emma M, Ryan, Anthony W, Conroy, Judith, Trimble, Valerie, Mahmud, Nasir, Kennedy, Nicholas, Corvin, Aiden P, Morris, Derek W, Donohoe, Gary, O'Morain, Colm, MacMathuna, Padraic, Byrnes, Valerie, Kiat, Clifford, Trynka, Gosia, Wijmenga, Cisca, Kelleher, Dermot, Ennis, Sean, Anney, Richard JL, McManus, Ross
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717209/
https://ncbi.nlm.nih.gov/pubmed/25920553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.87
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