Sex Steroids Do Not Modulate TRPM2-Mediated Injury in Females following Middle Cerebral Artery Occlusion(1,2,3)

Calcium-permeable transient receptor potential M2 (TRPM2) ion channel activation contributes to cerebral ischemic injury specifically in males. In male mice, circulating androgens are required for TRPM2 inhibition with clotrimazole (CTZ) to provide protection following experimental stroke. Sufficien...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Quillinan, Nidia, Grewal, Himmat, Klawitter, Jelena, Herson, Paco S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Disorders of the Nervous System
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596140/
https://ncbi.nlm.nih.gov/pubmed/26464961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0022-14.2014
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