Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

The generation of genetically-modified organisms has been revolutionized by the development of new genome editing technologies based on the use of gene-specific nucleases, such as meganucleases, ZFNs, TALENs and CRISPRs-Cas9 systems. The most rapid and cost-effective way to generate genetically-modi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ménoret, Séverine, De Cian, Anne, Tesson, Laurent, Remy, Séverine, Usal, Claire, Boulé, Jean-Baptiste, Boix, Charlotte, Fontanière, Sandra, Crénéguy, Alison, Nguyen, Tuan H., Brusselle, Lucas, Thinard, Reynald, Gauguier, Dominique, Concordet, Jean-Paul, Cherifi, Yacine, Fraichard, Alexandre, Giovannangeli, Carine, Anegon, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595769/
https://ncbi.nlm.nih.gov/pubmed/26442875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14410
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