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Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.

In vitro evaluation of a large chemical library of pharmacologically acceptable prototype compounds in a high-capacity, cellular-based screening system has led to the discovery of another family of human immunodeficiency virus type 1 (HIV-1) inhibitors. Through optimization of a lead compound, sever...

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Autors principals: Pauwels, R, Andries, K, Debyser, Z, Van Daele, P, Schols, D, Stoffels, P, De Vreese, K, Woestenborghs, R, Vandamme, A M, Janssen, C G
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC45949/
https://ncbi.nlm.nih.gov/pubmed/7680476
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